Medicinal Chemistry

Questions: 1. Consider, for instance, directing a microbiological examine where restraint of development of microorganisms is resolved when various centralizations of medications are applied. What variables may prompt fluctuation or blunders inside the outcomes and how could these varieties or mistakes be minimised?2. For what reason is it imperative to have data on physico-substance properties, (for example, logarithm of the octanol:water segment coefficient (log P) and log watery solvency (log S)) in tranquilize advancement for example what job do these properties play in deciding detailing and medication take-up/appropriation in the body?3. Is anticipating ADME and possible poisonousness of medication up-and-comers right off the bat in the medication improvement process significant or should the focal point of research be to boost viability of the up-and-comer atoms? Your answer ought to incorporate a conversation of the points of interest and restrictions of utilizing basic screening appara tuses, for example, Total polar surface territory (TPSA), infringement for Lipinskis Rule of Fives and number of rotatable securities might be utilized in screening and standardized event proportions (NORs), possible poisonousness and digestion? Answer: 1. Microbiological measures are generally directed in the lab to check the bacterial development restraint within the sight of various medication fixation. This can be acted in a plates containing development medium. Zone of comparability is found inside the plates, which speaks to the fixation at which a specific microbial development is repressed by specific medication (Zuccheri and Asproulis, 2012). Different variables may influence the outcomes. These are ill-advised planning of development medium, inappropriate choice of the populace number, imbalanced dampness, pH, supplement substance of the development medium. These mistakes can be limited by keeping up appropriate sterile condition during development medium arrangement, right determination of medication fixation. 2. LogP and logs coefficients are recognized as the most significant boundaries for lipophilicity evaluation, estimation of substance mixes dissolvability and assurance of pharmacokinetic properties. Inclination of particles to get break up in lipids is commonly determined as logP. Inclination of atoms to get break up in water lipids is commonly determined as logS (Sun, 2004). Along these lines, when a medication particle is created, it is a lot of fundamental to comprehend the essential property of that specific atom, regardless of whether that particle will be taken up by the human framework and conveyed appropriately inside a specific timeframe, consequently measurement of logP and logs is a lot of critical. 3. Expectation of assimilation, circulation, digestion and discharge and potential medication poisonousness at first during the medication advancement process is significant and the related research center ought to be made to amplify the adequacy of the competitor particle. This is on the grounds that it helps in foreseeing catalyst hindrance, for example, CYP3A4 Noninhibitor, CYP2D6 Noninhibitor, CYP2C19 Noninhibitor, CYP2C9 Noninhibitor, CYP1A2 Inhibitor. Fluvoxamine is a solid CYP1A2 Inhibitor and restrains a portion of the cytochrome P450 catalysts, as: CYP3A4, CYP2C9 and so on. Along these lines, fluvoxamine keeps not many metabolic pathways from rewarding for CYP1A2 hindrance. This sort of enzymatic restraint or non-hindrance can be anticipated with the assistance of screening apparatuses, which is considered as preferred position. Drawbacks may incorporate excessive adsorption techniques or network catching or covalent bound or immobilization strategies, low amount enzymatic a ction alongside the impediment of mass exchange. ADME properties incorporate ingestion, dispersion, digestion and discharge and potential medication harmfulness and these properties decide the medication manner once a medication goes into the framework. All out polar surface territory or TPSA of a competitor particle is distinguished as the whole of the surface over polar molecules, for instance: nitrogen, oxygen, including connected hydrogens (Chatwal, 2010). TPSA is utilized to upgrade the capacity of an up-and-comer medication to saturate cells. Particles with in excess of 140 squared are probably going to be poor at cell film penetration. Lipinskis rule of five assesses sedate likeliness and see if a synthetic compound with specific natural or pharmacological movement has trademark properties, which would make the intensify a normal orally dynamic medication in people. Generally orally expended drugs are similarly little and lipophilic particles. The benefit of Lipinskis decide of five is that it delineates the hugeness of certain sub-atomic properties for a specific medication pharmacokinetics inside the human framework. This incorporates ingestion, appropriation, digestion and discharge. The significant detriment of this standard is that it doesn't figure whether the applicant atom is dynamic pharmacologically. To foresee an up-and-comer particle, the nuclear condition in the applicant atom is determined and afterward database is looked for equivalent environmental factors. Event proportion quantifies how regularly the comparative encompassing has been found, contrasted and how much of the time it has been discovered altogether, and afterward is determined for singular particle in the competitor atom (Carlsson et al., 2010). This proportion present relative likelihood of digestion occurring at singular particle yet the drawback is that it doesn't anticipate whether the competitor atom experiences digestion. References Carlsson, L., Spjuth, O., Adams, S., Glen, R. furthermore, Boyer, S. (2010). Utilization of noteworthy metabolic biotransformation information as a methods for foreseeing metabolic locales utilizing MetaPrint2D and Bioclipse.BMC Bioinformatics, 11(1), p.362. Chatwal, G. (2010).Medicinal science. Mumbai [India]: Himalaya Pub. House. Sun, H. (2004). A Universal Molecular Descriptor System for Prediction of LogP, LogS, LogBB, and Absorption.Journal of Chemical Information and Modeling, 44(2), pp.748-757. Zuccheri, G. what's more, Asproulis, N. (2012).Detection of pathogens in water utilizing miniaturized scale and nano-innovation. London: IWA Publishing.

Running head Business ethics an Example of the Topic Business Essays by

Running head: Business morals Conceptual. With the ascent and development of free enterprise as a method of creation, and the push revenue driven boost, organizations have flooded forward into the corporate world with a point of limiting costs (, for example, the expense of work, and the operational expenses ), while simultaneously, augmenting the benefit. The above situation has prompted the huge instances of misuse of residents by the business world, driving likewise to the need to implement business morals. Specifically, there have been instances of extortion which thus came about to gigantic breakdown of eminence firms, for example, Tyco International, Enron, WorldCom, Peregrine Systems and Adelphia. It is this situation that prompted the formation of the Sarbanes-Oaxley 2002 Act to get improvements into this wild condition of advancements outfitted by human greed. Need article test on Running head: Business morals point? We will compose a custom article test explicitly for you Continue Understudies Very Often Tell EssayLab professionals:How much do I need to pay somebody to cause my task today?Specialists to exhort: Essaylab.Com Offers A Top-Quality Academic EssayBuy Essays Online Write My Essay For Me Grab My Essay Review University Essay Writing Service Be that as it may, with the requirement of the business morals and the Sarbanes-Oaxley 2002 Act, pundits have developed, refering to the symptoms of completing these specifications. It is against this scenery that this exploration paper has been composed, with the chief point of exhibiting how the traps brought up by pundits can be closed, so the Sarbanes-Oaxley 2002 Act can turn out to be increasingly successful. Presentation. The Sarbanes-Oaxley 2002 Act which is otherwise called the Public Accounting, Auditing and Investor Protection Act, the SOX or the Sarbox Acts was authorized in the Federal Law of the United States on 30th July 2002 as a reaction to the prevalence in the corporate and bookkeeping embarrassments. A portion of the organizations that had been influenced included Tyco International, Enron, Worldcom, Peregrine Systems and Adelphia. The outrages were so serious as a result, to a degree that billions of dollars of offer costs were relinquished, prompting the breakdown of these organizations and the ensuing dispersal of the national trust in security markets. The Act was named after its backers, Senator Paul Sarbanes and Representative Oxley G. Michael, after that the Act was affirmed by a 423-3 vote in the House and 99-0 in the Senate. This improvement was trailed by George Bush marking the bill into law, and in this way approving the most far reaching American business changes since the time the hours of president Franklin D. Roosevelt. The Act works by building up new and semi open organizations, for example, the Public Oversight Board for Accounting Companies (PCAOB) which is given the order of overseeing, reviewing, controlling and training all the bookkeeping firms that expect the job of examining the records of records for every open organization. The Act additionally reinforces ideas, for example, the autonomy of inspectors, interior control appraisal, corporate administration and simultaneously, upgrades the idea of money related exposure to general society. Research issue proclamation. Pundits, for example, Ron Paul (a Congressman), have countered that SOX Law was pointless because of the way that it hands the US firms a drawback in rivaling outside firms. The pundits keep up that a similar situation, achieved by the law has been liable for the heading out of organizations out of the US. Paul in his April fourteenth 2004 discourse in the US House of Representatives, was refering to the report by the Wharton Business School's discoveries. The clarity of these allegations are supported by the way that examination directed by the Wharton Business School discharged discoveries that, since the time the Sarbanes-Oaxley bill was passed into law, American organizations have been deregistering from the US Public Stock Exchange. Simultaneously, it was discovered that in New York for example, the New York Stock Exchange had just ten new participants into the financial exchange since the time 2004. Morals articulations. This exploration paper for the most part utilizes the utilization of scholastic books that have managed on the issue of business morals. Simultaneously, considerations that have been obtained, have been recognized to both keep away from instances of literary theft (scholarly robbery) and maintain the guidelines of scholarly morals. All the above measures have been considered, in the offer to show plainly the way that no legitimate business exercises can flourish without the perception of the business morals. Reason explanations. This examination paper looks for the most part to show the requirement for the perception of business morals in both the corporate area and the open segment. This paper does this by breaking down the difficulties that torment these segments because of not watching business morals. The examination paper does this by dissecting the Sarbanes-Oaxley Act under the setting of the US. Considerations on the best way to seal the escape clauses in order to completely understand the kindheartedness of seeing of business morals are examined moreover. Hugeness. This paper can be esteemed as important because of the way that it illuminates the advantages and disadvantages of receiving business morals (for this situation, the Sarbanes-Oaxley Act) by diving into the American setting. This isn't a conclusion to itself since this examination paper does this, while embracing the prevailing point of empowering the perception of Sarbanes-Oaxley Act as a type of business morals. The calibrating of the Sarbanes-Oaxley Act's modalities have likewise been managed on, in order to maintain a strategic distance from the irregularities and the doubts that pundits have towards the appropriation of Sarbanes-Oaxley Act as a type of business morals. Part 2 Writing audit. Studies have been done by various creators who all have various assessments about the significance of receiving the Sarbanes-Oaxley Act as a type of business morals. For example, the Wharton Business School (Manz, 2003 pp. 75) in its discoveries from an examination that it had directed in 2006, keeps up that the appropriation of Sarbanes-Oaxley Act as a type of business morals has just been instrumental in introducing dove development and advancement of the American Stock Market Exchange. The agents of this school point at the way that there has been a great deal of instances of deregistration of merchants in securities exchange. The Wharton Business School keeps up that this pattern has been continuing, after the marking into impact, the Sarbanes-Oaxley Act. The Korn-Ferry International in a similar frequency places that the execution of Sarbanes-Oaxley Act has just catalyzed the hesitance in favor of little scope organizations from entering the American Stock Market Exchange. Korn-Ferry International calls attention to this has been because of the way that 500 organizations have been accounted for to have lost a normal of 5.1 million as consistence cost in 2004 alone (De Vay, 2006 pp. 121). In a similar vein, Foley and Lardner law offices have as a reply to the above contentions against the selection of Sarbanes-Oaxley Act called attention to that the Act has just been extremely instrumental in expanding the costs of freely held or possessed organizations by 130% from the time the law was sanctioned. Foley and Lardner law offices proceed with that this situation has likewise prompted giving remote organizations an edge over nearby ones, because of the way that the Sarbanes-Oaxley Act tremendously rests its weights and orders on neighborhood business firms, contrasted with the outside firms. Different financial matters savants, for example, John C. Dvork (Hartman, 2004 pp. 84) additionally contend that the appropriation of Sarbanes-Oaxley Act prompts the smothering of inventiveness in the field of PC and innovation. Dvork proceeds with this is probably going to cause a downturn in the Information Technology area. Dvork, an innovation and registering writer clarifies this was seen in 2005 when the most seasoned and the most free client gathering of IBM reported its theories of shutting down, refering to the way that the approaches of Sarbanes-Oaxley Act was continually presenting it to inefficient agreement of assets. Part 3 Approach. This examination study action has been led predominantly by dissecting the academic books that have been composed on business morals comparable to the Sarbanes-Oaxley Act, and its underpinnings. Speculation. This paper has been composed to demonstrate that the appropriation of Sarbanes-Oaxley Act as a method of imparting the perception of business morals is just going to profit the US. This is to be realized by demonstrating unmistakably, both the upsides and downsides of embracing Sarbanes-Oaxley Act as a type of business morals. Causative examination. There are various reasons that hold up traffic of successful acknowledgment of business morals. A portion of these reasons are: Extra costs being forced on the organizations. High operational expenses particularly for the IT firms since buying in to the orders of the Sarbanes-Oaxley Act necessitates that these organizations update their frameworks. Simultaneously, these organizations are relied upon to overhaul their frameworks following the way that distinctive non IT firms rely upon IT frameworks and controls to actualize the specifications of the Sarbanes-Oaxley Act. The high pace of attack of remote business firms to the detriment of neighborhood organizations because of the way that the Sarbanes-Oaxley Act specifications are nation explicit, applying a lot of weight on the local firms. Part 3. Objectives and desires. It is normal that most of organizations in America will do well because of having bought in to the laws of business morals. This can't be a long way from reality, particularly if the measures are taken to seal the escape clauses of the Sarbanes-Oaxley Act. Simultaneously, the residents are additionally lik

Biking in Boston

Biking in Boston Summer hath come to Boston, as demonstrated by the fact that bitter cold has been replaced by stifling heat and humidity, with the two week interim comfort of spring gone all too quickly. I, however, love summer, for thats when I break out my bicycle. an actual photo of me with my bicycle (wikimedia)I began commuting by bike when I was in college, taking the Norwottuck Rail Trail from my house in Belchertown to school in Amherst or to see my girlfriend in Northampton. At the time, it seemed like a nice way to get outside, get some exercise, and get to places, but I never thought Id become committed to it. But though I hadnt ridden regularly since I was 10 or so, and my mountain bike was far too small and rusty to boot, I quickly fell in love with biking as a means of transportation. Once I moved to Boston I went to Wheelworks the best bike shop in the greater Boston area by far and picked up a nice, simple commuting bike. It set me back a few hundred dollars, but I like to think of that as just a few car payments, plus the health benefits accrued by exercise each morning. Ever since, Ive been biking to work every day that it is reasonably safe to do so, meaning any day during which the rain hasnt rain flooded the banks of the Charles (along which I bike) or which it isnt so cold that I could slip up on hidden snow or ice. Commuting via bicycle has several benefits, especially in a city like Boston. For one thing, its great exercise: I bike about 8 miles each way, which gives me about 35-40 minutes of a workout in the morning and afternoon. I arrive at work feeling refreshed and without the jumpiness associated with too little exercise. Its a timesaver, too, since my morning workout is wrapped up within my morning commute. Biking is also usually faster than any other form of transportation. The route to MIT from where I live in the suburbs has poor access to public transit and the roads are clogged worse than Elvis arteries. During rush hour, door-to-door via car is usually around 45 minutes; via bus, more like 60. Unless I hit all the wrong lights or get a flat, I can speed past all of them on my bike. Needless to say, its also greener assuming the increased calorie intake is offset and much, much less expensive. And as long as I shower at the Z Center before heading in to work, Im not even stinkier! Now, I know what you might be thinking: biking in a city? Why is this deeply psychotic and apparently suicidal man reading my college applications? Theres a smart way to bike, and a dumb way to bike. I bike very carefully, and almost entirely along bike trails that are off-the-road and devoted to cyclists. There are great regional bike maps not to mention Google Maps Biking layer that can tell you which roads are safe, which roads are unsafe, and the varying degrees in between. I always recommend driving (or walking, or busing) a route before bicycling it, because sometimes routes can be deceptive. For example, Massachusetts Avenue, which bisects the MIT campus, ostensibly has bicycle lanes on either side down its entire length; however, the placement of these lanes, sandwiched as they are between the main road and the side parking, makes them somewhat less safe than biking on the shoulder On the other hand, much of Vassar St (another road which bisects campus) has off-the-road bike paths newly installed in the last few years. If youre not a policy wonk, you may have missed Transportation Secretary Ray Lahoods new policy, which states that walking and biking should not be an afterthought in roadway design and will require states and municipalities competing for federal highway funds to include equal access for pedestrians and bicyclists. Translation: when roads get fixed in the future, they will be required to add safe, accessible bike lanes to facilitate commuting. So biking will only get better! I also love the bicycling culture. The bike shops in the area especially Wheelworks are all staffed by incredible people who are always happy to show you how to fix something or just hang out. The rear rack on my bike broke the other day, and I went down to Wheelworks and hung out for 45 minutes, borrowing tools and little bolts and getting my hands greasy on their shop floor. There are also some incredible opportunities for social improvement / justice through bicycling. You can get involved with Bikes Not Bombs, a nonprofit in the Jamaica Plain neighborhood of Boston of that works with disadvantaged youth in violent areas, both locally and internationally. BNB runs a bike shop and teaches kids how to fix bikes so they have something constructive to do rather than getting in to trouble. In the last 25 years theyve sent over 25,000 bikes to Ghana, Tanzania, Guatamala, New Orleans, and elsewhere. If youre on the West Coast, you may have heard of the Scraper Bike movement in Oakland. If you havent, you have to watch this short, wonderful documentary. If it doesnt change your life, it will at least change the way you think of bikes. In order to become a member of the Original Scraper Bike Team, you must: Be a resident of Oakland, CA. Be at least 7y/o or older. Retain A 3.0 Grade Point Average (GPA), Create your own Scraper Bike…(It Has To Be Amazing, Or Else You Can’t Ride.) A single-file line when riding. After 10 rides The Scraper Bike King and his Captains will decide if your bike is up to standards and if you can follow simple guidelines. After your evaluation we will consider you a member and honor you with an Original Scraper Bike Team Shirt. Only worn when Mobbin’ Stay posted to our website for all upcoming Scraper Bike Rides The Scraper Bike King Bikes can change health, commutes, communities, and the world for the better. Come ride with us!

Preventing Terrorism Government Control in Communication...

Surely the government should have some leeway over electronic communications, so as to prevent further terrorism. The fact that the terrorist attack on September 11th could have been prevented, had the information been accessed in time, exhibits the need for more government control in communication. According to Harris, â€Å"The Watchers† had all of the information needed to alert authorities of the incoming attack, but did not piece it together in time. These â€Å"Watchers† surely could have prevented the attack with more formidable access to the intelligence needed. Some would suggest that the intensive surveillance by the government could be turned in the favor of those wishing to attack us. Attacks such as this have taken place in Greece,†¦show more content†¦However, the government will not step out of bounds of the law in such monitoring conditions (Cornell). Additionally, a benefit of the government role in security through monitoring is the tracking o f current criminals or suspects. The electronic alternative to rehabilitation certainly cuts down on government revenue being poured into criminal cases. The electronic method significantly reduces the amount of taxpayer money going into the juvenile detention centers. Furthermore, this electronic alternative genuinely increases the success rate of the rehabilitation of previous criminals. The reason for this success is attributed to the familiarity and comfort while being allowed to stay in their own home, while still under government watch. The government can monitor the offender in real time, making sure that the terms of punishment are being met. The device that is worn broadcasts a signal which can be tracked very accurately, conveying the exact location of the wearer. This same technology is used to alert the local police if the offender is near a certain location, such as the house of a known rival, or a spot known to have illicit drug activity. This signal is automatically s ent out to alert the police of the exact position of the offender. The electronic method of surveillance in such cases is beneficial not only to the police who keep watch over the offenders, but also to the offender, offering a more comfortable alternative to sitting in a cellShow MoreRelatedTerrorism And The Social Media1719 Words   |  7 Pages Terrorism and the use of social media to further its objective is a major concern affecting the world today. With the growing threat of terrorism, studying its operational techniques help to determine how and why terror groups are succeeding. 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By disregarding cues of possible terrorist attacks and constant mistak es within the American Intelligence for not planning ahead, the United States failed to achieve its number one goal as a governing body: not keeping its citizens safe. It is important to dig into the issue of the disaster of 9/11 and completely understand the reason for failed prevention efforts. Moreover adding to these issues was the lack of communication and information

Analysis Of Jonathan Swift s A Modest Proposal And Li...

There are many uses of satire in Jonathan Swift’s A Modest Proposal and in Li Ruzhen’s Flowers in the Mirror. Both of these readings address social issues during the 17th and 18th century and address them with various uses of satire to help emphasize their thoughts of dislike and carry that to their readers. Jonathan Swift’s A Modest Proposal proposes using poor bastard children as food to help the poverty level along with other social issues that come with poor women carrying children and having to take care of them. Li Ruzhen’s Flowers in the Mirror gives a very detailed and eye opening view of a country where men and women’s roles in society are reversed to give readers and insight and different perspective of the social issues of how women are treated. To truly understand what Jonathan Swift’s A Modest Proposal and Li Ruzhen’s Flowers in the Mirror were trying to portray with the use of satire, a deeper look into the time era and s ocial issues of when it was written needs to be revealed and addressed. Jonathan Swift’s A Modest Proposal addresses issues with the poor Irish peasants that were too poor to feed their families. The British Government is partially to blame for the poverty as they exploited the Irish and never gave them a chance to come out of the poverty stricken routine that they were in. Swift has used satire in writings before, including Gulliver’s Travels, to get his points across of social unevenness. In A Modest Proposal Swift gives the idea of eating

Covey 7 Habits Analysis Free Essays

string(32) " when relating to your members\." I have always been a firm believer that there are many different types of leaders. To be a leader you must have natural ability, and have the ability to listen and grow. Being in many leadership roles and positions has helped me to become the best person that I can be. We will write a custom essay sample on Covey 7 Habits Analysis or any similar topic only for you Order Now Looking at leadership and management however opened my eyes to a new concept. I had never before realized how much the two go hand in hand. I feel the two words are synonymous in some aspects. My Leadership and Management style helped me to realize what kind of natural skills I have as a leader, and what kind of defined skills I have as a manager. My â€Å"Lamp† chart really was split between the two entities. I always thought that I was much more of a leader than a manager. Come to find out I have skills in both sides that compliment one another. My Leadership style consists of many components, but the main two are my creating abilities and my empowering abilities. I feel that these two are the natural traits that I have, and they are things that I have expanded on the more I learn about others, and myself. I have always been a creative person, the one with the ideas and new concepts. This has allowed me to be an effective leader in my positions to find other ways to do things, and to be successful at implementing new ideas. I also have the ability to empower those around me. What this means is to get people excited and willing to do whatever it takes to accomplish the goal or task we may face. I do this by believing in those around me and giving others the tools they need to lead themselves. My management style however is a bit different. I believe management skills are learned unlike leadership traits. Through the positions I have held on campus, in high school, an in the work place I have learned to become more responsible and in turn some vital managerial skills. Through my â€Å"LAMP† I have come to realize my top two managerial skills are organization, and I am very job centered. I have not always been an organized person, and still believe that there is much room for improvement. With that being said my organizational skills have vastly improved while in college and it is due to the roles I have had within clubs and organizations, and most importantly my fraternity. Organization didn’t come easy for me, but I realized to become an effective manager I needed to be organized, this directly translates to being an effective leader as well. Poor organization can lead to loss of credibility and that is something I try to stay away from. I am also very job centered. This means I like to know what needs to be done, by whom, and with a set date. If I have all of that I am able to delegate and get jobs finished in a timely manner. Being job centered really means I like to have defined roles. Who’s doing what is a big deal for me, especially in managerial and leadership positions. Now the question is are Leadership and Management the same? I think not. There is a reason that the two are separated on the test. Both Leadership and Management skills are vital when taking any role or position of power. The differences lie in how you take charge and take control. Leadership skills I feel are things you are born with. Leaders also are people who are highly revered, someone who you look up to or want to be. While Managerial skills can be taught if enough hard work and effort is put in. Yet managers sometimes are not revered as a role model because for the most part they tend to be your boss and make less of a personnel connection. This is why I feel having defined skills in both areas can make you the most effective person you can be. Being a great leader allows you to connect with people, excite people, and build credibility. While being a good manager means you delegate well, you stay organized and on task, and you oversee/stay on top of those whom you are managing. According to Kotter in the article What Leaders Do â€Å"Management is about coping with complexity. Leadership, by contrast, is about coping with change. † Good management is what keeps chaos from occurring. Kotter talks about how management is a major component in consistency and profitability if we look at it from a business aspect. This article describes how management is all about the complexities and how to good managers cope. â€Å"More change always demands more leadership. † (pg.. 86 Kotter. ) Things are ever changing today. This is why leadership as a practice has now become so important. Kotter talks about the abilities of leaders to run with the change and make things work with little room for discrepancy or chaos. A good leader is someone who can roll with the punches, figure out a new plan of action, and take charge all at once. Leadership is something that takes courage to make the tough decisions when something arises. The two styles although different do go hand in hand. When looking at Leadership and Management in relation to the Greek community we see how vital it is to have students who exemplify both qualities. When obtaining a Leadership role within a Fraternity or a Sorority you are taking a lot of responsibility. To run a Greek house you must have the support and respect from all members, otherwise you can accomplish nothing. Fraternities and Sororities were built on the basis that we share the same goals and aspirations, it is the Leaders job to remind everyone that so they are able to carry on together. Leadership skills also come in handy when relating to your members. You read "Covey 7 Habits Analysis" in category "Essay examples" If you approach them as a manager instead of their leader they may lose that connection with you. With that being said the Managerial side of running a Chapter also is very important. I like to think of this as the work side. When managing a Greek house you must always be on top of the logistical or behind the scenes work that many members never really get a chance to see, whether it be connecting with nationals, working with housing corp. , or going to IFC meetings. This is where being a manager plays a big role because with all of this work organizational skills, delegation, and planning all must take place otherwise mayhem could occur. Once things get out of hand it is hard to pull them back, that is why staying on top of everything as a manager is just as important as being the leader that everyone wants to follow. Another way to look at leadership and management in daily life is Stephen Covey’s book The Seven Habits of Highly Effective People. The book looks at how to be the most effective person you can be. The steps you need to take to do so is also a major component in the book. The 7 Habits prepares you to change your outlook on what it really means to be effective, and in turn what it takes to be a leader. Habit one is Be Proactive. Sounds pretty self-explanatory but when you look more in depth you can really learn a lot from this habit. Being proactive is the root to being effective. It is the first step away from dependence towards independence. Being proactive means taking initiative, getting things done, and overall taking control of your life. When you become proactive you take responsibility for your choices. You learn what it means to really take accountability and get things done. Being proactive really is all about getting yourself to do what needs to be done and being accountable for that. I have personally seen myself start to be more proactive the older I get. I was a huge procrastinator when I was younger and was always rushing to get things done. Now by being more proactive I have found time to do others things and take on more responsibilities as a leader. Habit two is, begin with an end in mind. This boils down to setting goals. Whenever starting a project or taking something over know what you want to achieve when you begin. This is very important in measuring success. If you have a goal you have a target you are trying to reach. The more solidified the goal the more prepared you can become while trying to achieve it. To begin with an end in mind is like setting a personal goal or mission statement that can be applied to everything that you do, thus knowing what you can and want to achieve. I find habit two extremely insightful. I have always been an activator, someone who loves to start things and get them off the ground, my problem sometimes is once I start I don’t know where to go. This habit is really on that I connected with because I feel it can help me solidify what I want to do and where I want to go when starting any project in my life. Habit three is put first things first. In other words it is to prioritize by importance rather than urgency. Many times people get caught up and procrastinate, leaving them behind and always rushing to catch up on due dates. In the book there is a chart called the time management matrix, which shows four quadrants. The ideal quadrant is two, if you are living in this quadrant you have your priorities in check and have some free time to enjoy life. Most people however live in quadrant one, which is crisis management and never having free time because of poor pre planning. I find this habit to be one of the more difficult ones to live by. In my â€Å"LAMP† planning was my lowest strength on the management side. I struggle with putting first things first because sometimes I literally do not put first things first. This is something since reading the seven habits that I know I need to work on for my own leadership and management needs. Habit four is think win-win. This chapter explains all the different types of people that are out there. It explains that some people are out there only working for the good of themselves and do not care if they push anyone down to get where they want. This chapter focuses on looking at life from the perspective of win-win. Therefore everyone is no worse off than before. If we always went into a deal looking for the best option for both parties then things would run a lot smoother. This habit teaches us that making the right call and doing the right thing will propel you further than if you are only looking out for your own self interest and nothing else. I feel that I am pretty acclimated with this habit. I have always been the type to seek mutual agreements on deals or trades. I feel that by both parties becoming better off there is more room for working together or trading again in the future. Someone who only looks out for themselves will end up burning many bridges and will have no one to rely on soon enough. Habit Five is seek first to understand, then to be understood. This means to listen to someone, really listen to someone. Habit five is all about understanding someone, fully listening and caring about what they say. In turn they will do the same for you. Empathetic listening is key when connecting and seeing where someone is coming from. This is a great characteristic to have as a leader. When someone feels like they are really being heard, then they will make a conscious effort to hear you out. This will in turn create an environment of complete unity and will make it that much easier to get things done when you can see from others points of views and they can see from yours. I feel that I have been getting better at understanding first then seeking to be understood. Many times during the beginning of my Presidency I would try to be heard first, what I noticed is that nobody listens when all you want is to be heard. Everybody has a voice and those voices need to have the opportunity to share. Once I learned this many people who I had never even connected with much before my term started coming to me for daily advice because I would actually listen to them. In turn I found myself with a mass support system within the house. Habit Six, Synergize. To combine the strengths of everyone in the group for cohesive and effective teamwork is what synergy is all about. You can also use synergy to bring all seven habits together as well. Once you can figure out a way to make them all work then the habits almost condense into one proactive effective lifestyle. To truly understand synergism you must understand and trust the process. The whole is greater than the sum of its parts is a great way to think about synergism. Working to combine the best attributes of people into one is very hard to do but with synergy you must trust others and trust yourself. Synergy can even be related to work, using synergistic energy to bring new ideas and methods is vital to keep things moving and to renew. I feel that because of my Leadership studies minor I have been able to see strengths in people and work together with them implementing my strengths to maximize the potential of the group and do the best job that we can. I also noticed that working as a team and feeding off of others ideas really gets the engines going, creating a better work environment and creating healthy competition. Habit 7, Sharpen the Saw. This is taking a step back, viewing where you are, your goals, and life and really taking the time to meditate and think of how you are effective, and more importantly how you can become even more effective. When you â€Å"Sharpen the Saw† you are taking the time to focus on you. This can even be things like working on your physical health and mental well being. This is very important because if you feel tired, overworked, or stressed it is time to re-evaluate everything and have a plan to better yourself. I like to think of sharpening the saw as if I am looking at my effectiveness and goals from an outsiders view and how I can grow to become a better leader. I feel that I do not take enough time to do this. , partially because I do not manage my time as well as I would like to, to really evaluate myself and how I am doing. I do find it is really difficult to revisit my strengths and weaknesses and how to improve them because I am too worried about how everyone else is doing. When looking at the seven habits and the move from dependence, to independence, and ultimately interdependence I see how the seven habits can really be effective. I found that the seven habits, if utilized correctly can really change your life. The book however in my opinion goes too in-depth about how to use the habits. I feel that it could be condensed, giving more information about the habit itself, and less about how to live your life. The habits should be interpreted by each person from their own standpoint because everyone will use them differently. The part of the book I connected with most was the circle of concern and the circle of influence. This really hit the nail on the head for me. I find myself worried about too much instead of figuring out ways to use my influence to change them. If I was less concerned, and more influential the problems I face would not be there in the first place. This is something I have tried to work on ever since reading Covey’s book. I also have become more aware of myself. Habit 7 opened my eyes to the fact that I really do need to take care of myself more. By doing this I can effectively use the other six habits to my advantage. Overall I found the habits to be a guide for how to not only be a leader, but how to live life. The habits themselves are great tools to use in a leadership position or to just become a better person. The habits paired with my strengths and my management styles really all coincide. Now I just need to take what I know, take a step back and see how I can apply it to my everyday routine. I want to live like my favorite quote says, â€Å"Don’t count the days, make the days count. † Muhammad Ali. The only way to make the days count is hard work, effort, and the application of my strengths and the seven habits. How to cite Covey 7 Habits Analysis, Essay examples

Photography Evolution Through Eps Cycle (Elite-Popular-Social Essays

Photography: Evolution Through Eps Cycle (Elite-Popular-Social In 1839 a process was invented that would forever change human perception and communication. Dubbed photography from the Greek words phos meaning light, and graphos meaning writing (Jeffrey, 240), the process was a much anticipated discovery. Long before its actual birth, the basic concept of of photography was common knowledge. It wasn't until the 1800s, however, that the idea of permenently fixing an image to a surface became tangible. Upon this discovery came the race to create the ?photograph.' Encoureged by a very eager middle class, early photography had many expirimentors. Two of which are credited as the fathers of the invention. Both of these fathers created photography simultaneously in 1839, announcing their success within three months of one another. Although each of these inventors imployed different techniques, the overall effect was the same, a permanently fixed photographic image. The first of the two technologies was the work of Louis Jaques Mande Daguerre. His method of photography incorporated the use of copper plates covered in light-sensitive chemicals as printable surfaces. Both the weight of the plates, as well as the availability of the chemicals kept photography out of the hands of the middle-class. This elite status, however, was short lived. Photography was the direct result of a demanding middle class causing a push for both inexpensive materials as well as simple devices. Photography did not spend much time in the elite stages of society. Instead the medium quickly evolved to accomodate a very eager public. Only ten years after its invention, a society of photographers was formed, organizing a profesion that was now becoming a fad. As one photo-historian explains: by 1851, ?pictures supplemented names, and identity became a matter of images rather than words? (Jeffrey, 241). Specialization of the medium took many forms, but it wasn't until 1880 that the most blatant of these forms surfaced. In 1880, the Daily Graphic, New York printed the first photographic image in its pages. By the early 1900s photo-journalism became a proffesion (Jeffrey, 243). As the 1900s progressed photography established itself as a solid a vital form of mass communication, both in print and exhibit. Bibliography Jeffrey, Ian. Photography: A Concise History. New York: Oxford University Press, 1981. Art Essays